Some of the safari options we organise:

Kruger Park Safaris from/to Johannesburg - already from 2 nights/3 days.
Recommended are 3 nights/4 days to boost your chances in meeting the "Big 5" in their natural habitat.

Safaris in the Pilansberg Nationalpark (Near Sun City) from/to Johannesburg. (malariafree)

Safaris in the Addo Elephant Nationalpark or in one of the many Private Game Reserves within the Eastern Cape Province.
(The Eastern Cape is malariafree), e.g. "Shamwari Private Game Reserve."

Safaris along the Garden Route area.
our recommendation: Bottlierskop Private Game Reserve. (malariafree)

Safaris in Northern Kwa Zulu Natal - Hluhluwe/Umfolozi Park,
iSimangaliso Wetlands Park, Pongola or Ithala Game Reserves.

Safaris in Botswana (Okavango Delta, Moremi, Savuti, Chobe, etc.)

Safaris in Zimbabwe (Victoria Falls)

Safaris in Namibia (Etosha Nationalpark)